HCV (Yofulumira)

Odwala ambiri alibe zizindikiro zoonekeratu pachimake siteji ya matenda, limodzi ndi kuchuluka kwa viremia ndi ALT kukwera.HCV RNA idawonekera m'magazi kale kuposa anti HCV pambuyo pa matenda oopsa a HCV.HCV RNA imatha kuzindikirika patatha milungu iwiri itatha kuwonekera koyambirira, HCV core antigen imatha kudziwika patatha masiku 1 mpaka 2 HCV RNA ikuwonekera, ndipo anti HCV sangadziwike mpaka masabata 8 mpaka 12, ndiye kuti, pambuyo pa matenda a HCV, pali pafupifupi. Masabata a 8-12, HCV RNA yokha ndi yomwe ingadziwike, pamene anti HCV ndi yolakwika, ndiye kuti, "windo lazenera" la anti HCV kuzindikira, ndi kutalika kwa "windo lazenera" likugwirizana ndi reagent (onani Table 1). ).Anti HCV si anti-antibody yoteteza, koma chizindikiro cha matenda a HCV.15% ~ 40% ya odwala omwe ali ndi kachilombo koyambitsa matenda a HCV amatha kuchotsa matendawa mkati mwa miyezi 6.Pochotsa matendawa, mlingo wa HCV RNA ukhoza kukhala wochepa kwambiri kuti udziwike, ndipo anti HCV yekha ndi yabwino;Komabe, 65% ~ 80% ya odwala sanachotsedwe kwa miyezi 6, yomwe imatchedwa matenda osatha a HCV.Kachilombo ka matenda a chiwindi C kakachitika, HCV RNA titer imayamba kukhazikika, ndipo kuchira kodziwikiratu sikochitika.Pokhapokha ngati chithandizo chamankhwala chopha mavairasi chikuchitika, kuchotsedwa kwa HCV RNA modzidzimutsa sikumachitika kawirikawiri.M'zochitika zachipatala, odwala ambiri omwe ali ndi matenda a chiwindi C amakhala ndi anti HCV (odwala omwe ali ndi kachilombo ka HIV, omwe ali ndi kachilombo ka HIV, olandira ziwalo zolimba, odwala hypogammaglobulinemia kapena odwala hemodialysis angakhale opanda anti HCV), ndipo HCV RNA ikhoza kukhala yabwino. kapena zoipa (mulingo wa HCV RNA ndi wochepa pambuyo pa mankhwala oletsa tizilombo toyambitsa matenda).